Prior to October 2008, ISAF had played an indirect role in the fight against opium in Afghanistan only through joint information with the Afghan government, the protection of Afghan poppy eradication units, and assistance in coordinating and implementing the country`s anti-drug policy. Thus, Dutch soldiers used military force to protect the extermination units attacked. ISAF military casualties and civilian casualties caused by the Coalition/ISAF war and friendly fire have become an important political issue, both in Afghanistan and in troop-contributing nations. More and more civilian casualties have threatened the stability of President Hamid Karzai`s government. That is why, as of July 2, 2009, the coalition has ordered air and ground operations to take steps to minimize Afghan civilian casualties, in accordance with a tactical directive from General Stanley A. McChrystal of the United States, commander of the International Security Assistance Force in Afghanistan.  Prisoner operations. Effective prisoner operations are essential to success. The ability to keep insurgents away from the battlefield is essential to ensure effective protection of the population. In addition, the precision required by counter-insurgency operations must be ensured by the intelligence services; The intervention of inmates is a critical part of it. It is also necessary to obtain accurate information and evidence of detainees during military operations in order to support rule of law and reintegration programmes and to ensure that only insurgents are detained and that civilians are not over-affected. Coalition forces are working without a bilateral agreement with the Afghan government.
This gives them room for discretion to act in line with U.S. objectives and interests. However, the Karzai government`s agreement to continue the operation provides legal support for the operation. President Karzai called on coalition forces to focus more on insurgent supply lines and bases in Pakistan, indicating a difference in the perception of Afghanistan`s vital interests by the United States and the Afghan government. Karzai also called on the United States to reduce unpopular actions such as searches and bombings in Afghanistan. Appendix II of the Bonn Convention on the « role of the United Nations » stipulates that the Special Representative of the Secretary-General is responsible for all UN activities in Afghanistan as well as for « monitoring and implementation assistance » of all aspects of the Bonn Agreement (Annex II). The United Nations was asked to « advise » and assist the Afghan transitional authorities and to participate in government meetings. The annex also states that in the event of an impasse between members of the transitional government, the SRSG « could use its good offices to facilitate a settlement of the impasse or a decision. » Regional commandos coordinate all regional civilian and military activities carried out by PRT military elements in their area of expertise, under the operational control of ISAF. Each regional command is supported by a governing nation and consists of a Command and Control HQ and an Advance Assistance Base (FSB), which are essential logistics facilities that have been created to provide a node of care, medicine and transportation in each region to support PRTs.
FSBs are also used to house rapid response forces and tactical operations centres.